
Maintenance and Troubleshooting 5
8000 Operator’s Manual 113
12 Install the new seal into the syringe port, making sure that it lays flat
in the bottom of the port and that the media path is not obstructed.
13 Install the syringe into the valve. Tighten by hand (18 - 21 oz-in,
1.3 - 1.5 Kg-cm).
14 Extend syringe plunger so that it is aligned with the plunger pin on
the pump.
15 Carefully install the syringe and valve assembly onto the valve and
plunger pins.
16 Replace the syringe valve retainer block and tighten the screws.
17 Reinstall the syringe plunger thumb screw(s).
18 Place the pump upright and connect the power cord and
communication cables.
19 Turn on the pump.
20 Connect all sample tubes to the pump.
21 Check for leaks using the 8000.
Cleaning the Syringes
To clean the syringes, use the appropriate cleaning solution based on the
product being tested. Ensure the sampling cannulas of the dissolution
apparatus are submerged into the cleaning solution. Syringes should be
cleaned after each test using one of the following procedures:
50% Methanol or 10% Bleach Cleaning Procedure
1 From the 8000 Ready screen, press MENU > 7. The Manual
Operations screen displays.
2 Select option 6, Syringe/Filter. The Operate Syringe/Filter Changer
screen displays.
3 Select option 1, Valve to Input, to ensure the valve is set to input.
4 Select option 3, Syringe Fill.
The pump will initialize and compress all of the syringe plungers when
turned on.
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